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management rheumatology dermatology differential sle syndrome erythematosus oncology symptoms systemic vasculitis algorithm classification photo causes cryoglobulinemia disorders fungal hemophagocytic hlh
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
infection Malar ... infection • Lyme ... disease • Rosacea ... lesions • Discoid lupus ... #differential #diagnosis
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... organ-specific signs ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
inflammatory cells) Clinical ... : • Disease fatal ... exertion • Neurologic ... neuropathies • Skin ... #Symptoms #Signs
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Neurological 12% ... Other auto-immune, Infectious ... diseases, Hematological ... autoantibodies #signs ... #differential #rheumatology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
cryoglobulinemia vasculitis - Diagnosis ... cryoglobulinemia vasculitis Clinical ... manifestations - Skin ... neuropathy Treatment ... with refractory disease
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Arthralgia/arthritis, Skin ... Differential Diaqnoses ... : • Infectious ... #treatment #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... • Immunologic Workup ... Evolution: Chronic disease ... #diagnosis #management
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