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diagnosis management oncology deficiency rheumatology disease erythematosus lupus pathophysiology refeeding sle systemic agglutinin algorithm aplastic arteritis atrophicglossitis autoantibodies behcet candida
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
• Vitamin E - Haemolytic ... Wernicke-Korsakoff syndrome ... Vitamins #Deficiency #differential ... #diagnosis #signs ... #symptoms #nutrition
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... syndrome (ST-HUS ... crisis • Severe B12 ... anemia" • HELLP ... #diagnosis #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Nutritional ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... diarrhoea, Short bowel syndrome ... dental fixatives, Treatment ... Haematological: Anaemia ... #riskfactors #symptoms
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... blood loss, Acute hemolysis ... , deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... of anemia include ... anemia • Cold ... younger pts) Differential ... #anemia #hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
in Cirrhosis - Differential ... PRODUCTION • Vitamin B12 ... Destruction: Zieve's syndrome ... anemia, Hemolysis ... #Diagnosis #Hepatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... autoantibodies #signs ... #symptoms #mimickers ... rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
- Little or no nutritional ... -DPG -> - hemolysis ... - anemia ... pathophysiology #symptoms ... #signs
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