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management differential syndrome algorithm dermatology lupus ana workup anemia classification erythematosus systemic patterns vasculitis antibody joint pain thrombocytopenia antibodies arthritis
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
SHARP - Lupus Diagnosis ... Discoid Rash A Antinuclear ... Arthritis R Renal Disease ... #IMDAMNSHARP #sle ... erythematosus #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Erythematosus - Summary Antinuclear ... • Specific for SLE ... Treatment: • ... #Summary #diagnosis ... #rheumatology #
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... , OJ, PL-7, PL-12 ... #differential #diagnosis ... #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... in drug-induced SLE ... Jcortesizaguirr #ANA #Antinuclear ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Adult Onset Still's Disease - Yamaguchi Criteria Major criteria: - Fever >= 39C lasting >= 1 weeks
- Fever >= 39C lasting ... - Arthralgia lasting ... rheumatoid factor or antinuclear ... Yamaguchi #Criteria #Diagnosis ... #Major #Minor #Rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... disorders • Celiac disease ... effect following treatment ... #Hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Human parvovirus B19 ... Malar rash • SLE ... IBD • RA • SLE ... #differential #diagnosis ... #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Megakaryopoiesis • B12 ... Autoimmune • ITP • SLE ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Splenomegaly - CTD (SLE ... Associated - SLE ... #Differential #Diagnosis ... #hematology #rheumatology
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