46 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Chemotherapy) ... Megakaryopoiesis • B12 ... Autoimmune • ITP • SLE ... Algorithm #Causes #Hematology
Treatment of breast cancer: a simplified view
surgical therapy - 5-7 weeks
 - lumpectomy +
 - radiation
Treatment of breast ... mastectomy systemic chemotherapy ... - 12 weeks - ... breast #cancer #treatment ... timeline #simplified #oncology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
dysmotility • MCTD (SLE ... • Specific for SLE ... Treatment: • ... Erythematosus #SLE ... Summary #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Human parvovirus B19 ... Malar rash • SLE ... infection • Lyme disease ... IBD • RA • SLE ... differential #diagnosis #rheumatology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia, Chronic disease ... Macrocytic RBC: Vitamin B12 ... deficiency, Liver Disease ... , MDS, Chemotherapy ... differential #diagnosis #hematology
Dyspnea - Considerations with Malignancy
Directly Malignancy Related:
 - Lymphangitic spread to lung
 - Malignant pleural effusion
metastases Treatment ... Related: - Chemotherapy ... Radiation induced disease ... differential #diagnosis #oncology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
Hansen's Disease (Leprosy)
 • Transmission - not completely understood, ?nasal droplets
 • Symptoms appear ~5 years
Hansen's Disease ... Immunosuppression (e.g., chemotherapy ... and numerous AFB Treatment ... 600mg daily x 12 ... diagnosis #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... inducers #inhibitors #Chemotherapy ... #Oncology #Hematology ... Interactions #Table #Pharmacology