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management oncology differential algorithm leukemia syndrome aplastic causes chronic cll comparison lymphocytic mds myelodysplastic pharmacology workup abscess activation apml atlas
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... B-symptoms, bruising/bleeding ... hepatomegaly • Labs: anemia ... predominant immature cells ... #Algorithm #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
• Sickle cells ... Liver diseases, Bleeding ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... #diagnosis #management ... #treatment #hematology
Managing warfarin INR Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... #pharmacology #treatment ... #medications #table ... #decisionaid #cardiology ... #hematology #warfarin
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... ecchymoses, mucosal bleeding ... Treatment: ... #oncology #hematology ... #diagnosis #management
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Pelger-Huet, Macrocytic anemia ... or λ), Smudge Cells ... Blood #Disorders #hematology ... #Differential #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... factor (GCSF) treatments ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... 5) Symptoms of anemia ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Schistocytes, helmet cells ... Treatment: ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
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