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diagnosis management differential oncology sle reactions classification erythematosus hcq hydroxychloroquine pharmacology product table transfusion treatment vasculitis workup adverseeffects algorithm anemia
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... autoantibodies that will cause ... inflammation, leading ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Systemic Lupus ... Leukemia - History of Bleeding ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
intake) • Target blood ... Insufficient blood ... • Special cases ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... or if a primary hematologic ... #Workup #hematology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... 3) Limb oedema leading ... pericarditis » is...lupus ... Lupusreference #lupus ... erythematosus #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... cases, drug-dependent ... Discontinuation of causal ... #sle #comparison ... #table #rheumatology
Helpful Clues for Distinguishing Upper vs. Lower GI Bleeding Upper GI Bleed (proximal to ligament of Treitz):
Helpful Clues for ... Lower GI Bleeding ... supporting feature: Blood ... Lower #GIBleed #comparison ... versus #diagnosis #gastroenterology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Findings: • Bleeding ... ABO incompatible blood ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... other medications leading ... rare with ~100 cases ... Risks #Benefits #Lupus ... #sideeffects #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... -> AML: Blast crises ... #Leukemia #Hematology
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