27 results
diagnosis differential management oncology algorithm sle dermatology erythematosus bruising classification hcq hydroxychloroquine pharmacology product rash reactions systemic treatment workup adverseeffects
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... • Steroids • Vasculitis ... Coagulation #Bleeding ... Diagnosis #Algorithm #Causes ... #Hematology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... ANCA associated vasculitis ... (RA), Systemic lupus ... (SPA) • Other Causes ... Differential #Diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... autoantibodies that will cause ... inflammation, leading ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Systemic Lupus ... Leukemia - History of Bleeding ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... Water - Pus - Blood ... Pulmonary HTN - Vasculitis ... syndrome Other Causes ... Transverse myelitis • Hematology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
intake) • Target blood ... Insufficient blood ... • Special cases ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Butterfly rash, Vasculitis ... Glomerulonephritis Myositis(5%) Blood ... Thrombocytopenia #Lupus ... symptoms #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... or if a primary hematologic ... #Workup #hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... such as systemic lupus ... pulses, bruis, or blood ... Large Vessel: Blood ... differential #diagnosis #rheumatology
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