20 results
diagnosis management differential erythematosus systemic treatment vasculitis workup arthritis classification disease pharmacology product reactions acid aortitis approach cerebritis clues cns
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... intake) • Target blood ... Insufficient blood ... #rheumatology # ... pharmacology #levels #lupus
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... inflammation, leading ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Inhibits plasminogen activation ... reduces complement activation ... Hemoptysis, GI Bleeding ... diarrhea & abdominal pain ... #Pharmacology #hematology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... 3) Limb oedema leading ... #diagnosis #sle ... erythematosus #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... lesions Abdominal pain ... Glomerulonephritis Myositis(5%) Blood ... symptoms #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... purpura to mucosal bleeding ... erythematosus [SLE ... Diagnosis #Management #Hematology ... #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... test, ANA (e.g., SLE ... #Workup #hematology
Sickle Cell Disease - Pathophysiology of disease and complications Due to the deformed shape, HbS induces
membrane damage leading ... membrane proteins and activating ... obstructing and reducing blood ... , necrosis and pain ... Complications #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... Arthritis: • Joint pain ... Chronic B-cell activation ... Erythematosus #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... erythematosus (SLE ... (SPA) • Other Causes ... Differential #Diagnosis #rheumatology
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