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diagnosis rheumatology differential classification erythematosus management activation algorithm ana anca antibodies antibody antineutrophil antinuclear aortitis approach arthritis cerebritis clues cns
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... • Steroids • Vasculitis ... Coagulation #Bleeding ... #Hematology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... ANCA associated vasculitis ... (RA), Systemic lupus ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... inflammation, leading ... Erythematosus #SLE ... CNS #neurology #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... erythematosus (SLE
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... inhibitor and lupus ... discern these causes ... integrity == • Vasculitis ... Differential #Diagnosis #Hematology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... 3) Limb oedema leading ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... in drug-induced SLE ... ANCA-Associated Vasculitis ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... -> AML: Blast crises ... PLT: Petechiae, bruising ... lymphocytic lymphoma (SLL ... #Leukemia #Hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... (systemic lupus ... infections - Vasculitis ... #Causes #peds #
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