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Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
proliferative blood disorders ... #Algorithm #classification ... #leukemia #hematology ... #oncology #diagnosis ... #CML #CLL #AML
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... and Differential Diagnosis ... Pelger-Huet, Macrocytic anemia ... #hematology #Markers ... #Differential #Diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... stem cell transplant ... #treatment #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
fever, joint pain, bleeding ... night sweats, bleeding ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Lymphoproliferative disorder ... , Autoimmune disorder ... Spherocytes • Treatment ... transient hemolysis • Treatment ... #hematology #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... • Rheumatic disorders ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... 80-100 fL) • Bleeding ... #MCV #Classification ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... #Classification ... Algorithm #Causes #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... factor VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... changes), high MCV anemia ... not required in all ... Causes #Workup #hematology