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causes hematology algorithm hyperkalemia potassium classification infections deficiency disease druginduced drugs erythematosus g6pd hemolytic infectiousdiseases laboratory lupus nephrology pulmonary rheumatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... Chronic Infection) High ... #Diagnosis #Algorithm
Drugs Implicated in Hemolytic Anemia • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Anemia • Hapten ... Bloodman #Drugs #medications ... #Hemolytic #Anemia ... #differential # ... diagnosis #pharmacology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... • Present in high ... Dehydrogenase #Elevated #differential ... #diagnosis #Laboratory
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
High Glucose ... blood loss • Hemolytic ... anemia • Splenomegaly ... Increase #Decrease #Diagnosis ... #DM2 #Differential
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... phlebotomy High ... Medications 2. ... #potassium #high
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... Diagnosis: • hemolytic ... anemia • Cold ... younger pts) Differential ... • Symptoms: High
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... phlebotomy High ... Medications 2. ... #potassium #high
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperuricemia - Differential ... Diagnosis Algorithm ... Leukemia (CML) - Hemolytic ... Anemia - Others ... Drug-induced • High
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... blood loss, Acute hemolysis ... , deficiency anemia ... • Reaction to Medications
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
in Cirrhosis - Differential ... Diagnosis Framework ... Inflammation NORMAL / HIGH ... , Autoimmune hemolytic ... anemia, Hemolysis
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