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90% - Low
complement
... constitutional symptoms •
Treatment
... Discontinuation of
causal
... 80% - Low
complement
... life-threatening •
Treatment
Selected Diseases on
Complement
... Levels - C3, C4 •
SLE
... • Infection eg
SBE
... ThePeanutKidney #
Complement
Erythematosus (
SLE
... are evocative of
SLE
... Positive in 60-80% of
cases
... 80% - Low
complement
... life-threatening •
Treatment
Causes
of Hemolytic ... Antibody/DAT+ -
Complement
... Differential #Diagnosis #
Causes
Mechanism: IgG and
Complement
-mediated ... Spherocytes •
Treatment
... Mechanism: IgM and
Complement
-mediated ... transient hemolysis •
Treatment
dysmorphic RBC, RBC
casts
... staining (lg +
complement
... MGPN •
Complement
... of alternative
complement
... MPGN without
complement
Erythematosus (
SLE
... HLA-DR3 genes,
complement
... self-antigens, activating
complement
... Erythematosus #
SLE
anti-GBM) 10%: - Low
Complement
... Levels:
SLE
, Cryoglobulinemic ... Vasculitis - Normal
Complement
pathophysiologic
causes
... staining): • Low
Complement
... Idiopathic • Normal
Complement
Occult
Causes
of ... hypotension is
treatment
... response -> cognitive
pause
... toxicologic - 2nd
cause
... #Differential #
Causes
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