34 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Differential ... #Hypokalemia #Differential ... #potassium #low ... #pathophysiology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Hypertensive: • High Al ... #Hypokalemia #Differential ... Algorithm #nephrology #causes ... #low #potassium
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
sodium, which causes ... inhibiting drug classes ... Antagonists), all ... , just like all ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... #Hyperkalemia #Differential ... Diagnosis #Algorithm #causes ... #potassium #high ... #pathophysiology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... number of pain crises ... vs. 1) • Fewer ACS ... Benefits #SickleCell #pathophysiology ... #pharmacology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... intracellular calcium causes ... CaitEKulig #Digoxin #Pharmacology ... #Pathophysiology
Mucoid Degeneration of the ACL
Imaging Findings:
 • T2-hyperintense fluid-signal within the enlarged ACL on both the
• The anterior cruciate ... Case description ... Differential Diagnosis ... cyst (cruciate ... - Can cause
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... Edema #Medication #Causes ... #Differential # ... Pharmacology #Pathophysiology