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diagnosis differential algorithm causes management rheumatology liver disorders hepatitis injury oncology approach arthritis ascites pain pathophysiology thrombocytosis treatment acid base
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Acute hemolysis ... Severe trauma, Acute ... Diagnosis #Algorithm #hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
- Anemia of chronic ... of chronic kidney ... disease - Vitamin ... Underproduction #Algorithm #hematology ... #differential #workup
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
of chronic kidney ... disease, Acute ... Alcohol use, Liver disease ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Infectious: • Acute ... or Chronic Inflammatory ... disorders • Celiac disease ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... Myelodysplastic syndrome ... Malignant tumors, Acute ... Hemolytic uremic syndrome ... #differential #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... hemorrhage) • Chronic ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Acute sickle cell ... crisis: • Fever, acute ... of SCD crisis Acute ... hepatomegaly and anemia ... Hepatobiliary #hepatology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... #Normocytic #Anemia ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
of chronic inflammation ... deficiencies: Chronic ... kidney disease, ... Index > 3: • Acute ... Production #Index #hematology
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