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diagnosis management differential rheumatology causes oncology algorithm dermatology disease cardiology hepatology nephrology thrombocytosis aki cancer chronic classification indications laboratory leukemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
: Acute blood loss ... , Acute hemolysis ... , deficiency anemia ... infections, TB, Acute ... Severe trauma, Acute
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Infectious: • Acute ... Non malignant hematologic ... effect following treatment ... states • Non-hematologic ... Iron deficiency anemia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... transformation to acute ... only curative treatment ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Treatment: • Consider ... progress to MDS or acute ... diagnosis #management #treatment ... #hematology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Cell Disease Acute ... crisis: • Fever, acute ... Supportive with treatment ... of SCD crisis Acute ... hepatomegaly and anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Myelodysplastic syndrome ... Malignant tumors, Acute ... Hemolytic uremic syndrome ... #differential #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... kidney disease, Acute ... blood loss, Anemia ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Algorithm for the Evaluation ... Causes of acute ... Irritable bowel syndrome ... Malabsorption syndromes ... management #algorithm #workup
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... High in acute blood ... for degree of anemia ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
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