16 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... cases, drug-dependent ... Workup: - ANA ... Workup: - ANA
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... disease (MCTD), Drug-induced ... (SLE), Systemic ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Workup: - ANA ... life-threatening • Treatment ... #lupus #Systemic ... Management #Summary #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... lupus erythematosus ... Anti-histone (in drug-induced ... SLE) • Systemic ... antibodies #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
) ANA or Anti-NucIear ... • +ANA can be seen ... (SLE), Systemic ... (SLE), Systemic ... #patterns #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... severe disease Treatment ... #Lupus #Erythematosus ... diagnosis #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... searched for when ANA ... (60-70%) & drug-induced ... #diagnosis #rheumatology ... #table #ANA
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
pericarditis (search ANA ... pleurisy (search ANA ... person (search ANA ... cytopenia (search ANA ... #clues #system
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Auto-Antibodies: - ANA ... Mimickers: Drug-induced ... #Systemic #Lupus ... #differential #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... < 30 years - Aorta ... LFT • ESR • ANA ... vasculitis, and SLE ... differential #diagnosis #rheumatology