361 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... • Elevated D-Dimer ... • PTT: ↑ • D-Dimer ... Treat primary cause ... Coagulation #diagnosis #causes
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
D-dimer Plasma ... D-dimer is a product ... Elevated plasma D-dimer ... D-dimer has been ... age, which can cause
Common causes of sciatica. Disc herniation is the commonest cause. Spondylolisthesis can cause impingement #Anatomy #Pathophys
Common causes of ... Disc herniation ... the commonest cause ... Spondylolisthesis can cause
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... platelet count, D-dimer
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation (DIC ... INR use PT D-dimer ... small vessels #DIC
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
fibrinogen levels, D-dimer ... decompensated DIC ... Diagnosis #Honc #DIC
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... intravascular coagulation (DIC ... MAHA: TTP, HUS, DIC
Pathological Optic Disc Cupping

Note cup-to-disc ratio at least 0.8 (physiologic limit of 0.5).

Thinning of optic disc
Pathological Optic Disc ... Note cup-to-disc ... so that optic disc ... Usual cause is glaucoma ... Glaucoma causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... • Secondary Causes ... marrow disease - DIC ... Coagulation Defects: • DIC ... Purpura Fulminans (DIC
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... • TTP/HUS • DIC ... Diagnosis #Algorithm #Causes