63 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
and Treatment Algorithm ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis ... #management #algorithm
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
- Differential Diagnosis ... Primary: - CML ... Hypereosinophilic Syndrome ... #Differential #Diagnosis ... #Causes #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... glucocorticoid treatment ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... and Management ... #diagnosis #hematology ... #differential #management
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... #diagnosis #management ... #treatment #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... for Anemia (Morphological ... Myelodysplastic syndrome ... #differential #diagnosis ... #causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... 1) DIAGNOSE AIHA ... • Anemia: macrocytic ... #diagnosis #management ... #treatment #rheumatology
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Arthritis Summary MCP ... Tunnel, Sicca Syndrome ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms