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management rheumatology sle dermatology erythematosus syndrome differential microbiology oncology american chagas comparison scleroderma signs summary sweet symptoms table testing trypanosomiasis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Treatment: • ... #Lupus #Erythematosus ... #SLE #Summary #diagnosis ... #rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Cerebrovascular Disease ... permeability Diagnosis ... #cerebritis #diagnosis ... #management #treatment
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... Symptoms: • Cardiac ... interstitial lung disease ... #diagnosis #signs ... symptoms #testing #workup
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... solid cancers • Systemic ... , DIC, TMA • Cardiac ... #diagnosis #management ... #treatment #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... 5% of patients Cardiac ... Cytopenias • Cardiac ... #Diagnosis #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... lupus erythematosus ... scleroderma) - Anti-Scl ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... months to years) Systemic ... • Immunologic Workup ... Evolution: Chronic disease ... #diagnosis #management
Tularemia - Diagnosis and Management Summary Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection •
• Typhoidal: Systemic ... Culture & GS, PCR ... Treatment: ... • Severe Disease ... #infectiousdiseases
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary Acute Chagas Disease (8-12 weeks): • Mild: Malaise,
• Treatment: ... PCR not useful for ... clinical evidence of cardiac ... clinical evidence of cardiac ... #Microbiology #InfectiousDiseases
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