ecg qtc syndrome acltear hematology disease differential classification causes diagnosis hepatology liver anemia hemolytic algorithm elevatedmcv hemolysis cvid

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Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

for Hemolysis - ... Intravascular Hemolysis ... Microangiopathic hemolytic ... #differential # ... diagnosis #hematology

Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80

Causes of Anemia ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... Diagnosis #Algorithm ... #Causes #Hematology

Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
- Decreased/NormaI

Causes of Anemia ... Diagnosis Algorithm ... Bleed • Hemolysis ... Diagnosis #Algorithm ... #Causes #Hematology

Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
•

Causes of Anemia ... Diagnosis Algorithm ... #elevatedMCV #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology

Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),

Microangiopathic Hemolytic ... spherocytosis, Autoimmune hemolytic ... Cold autoimmune hemolytic ... RBC #Morphology #differential ... #diagnosis #hematology

Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
• Thalassemia

to Anemia - Differential ... -100): • Non-hemolytic ... , CKD • Hemolytic ... disease, Alcoholism ... Diagnosis #hematology

Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
• Enzyme deficiencies ex. G6PD, pyruvate kinase
• Hemoglobinopathies

Differential Diagnosis ... for Hemolytic Anemia ... : • Liver disease ... #Anemia #Differential ... #hematology

Red Blood Cell (RBC) Morphology Atlas
• Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning

, Liver diseases ... spherocytosis, Hemolytic ... , Liver diseases ... Schistocytes - Hemolytic ... hematology

Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
• Bacterial
• Viral (EBV)
• Parasitic
• Fungal
Congestive

- Differential ... Diagnosis Algorithm ... Serum Sickness Hemolytic ... #Diagnosis #Algorithm ... #Causes #Hematology

Hemolysis - Differential Diagnosis Framework

1) Environment
- Fragmentation
- MAHA: TTP, HUS, DIC, HELLP

Hemolysis - Differential ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... Urobilinogen #Hemolysis ... Diagnosis #hematology

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