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diagnosis management differential algorithm causes rheumatology hepatology dermatology syndrome disease oncology pharmacology idsa clinical hivaids opportunistic prevention cardiology classification hemolytic
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Hypersplenism, Infection ... #Hemolytic #Anemias ... Diagnosis #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelofibrosis Infectious ... Non malignant hematologic ... effect following treatment ... states • Non-hematologic ... Iron deficiency anemia
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Infiltration: • Hematologic ... and non-hematologic ... malignancies • Infection ... Toxins • Aplastic Anemia ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
infiltration (e.g ... . cancer, infection ... Marrow suppression (e.g ... G6PD deficiency), Infections ... Production #Index #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... : • Recurrent infections ... Treatment: • Consider ... diagnosis #management #treatment ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... differential #diagnosis #hematology ... #anemia
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... deficiency) • Infection ... Sepsis • Non-infectious ... causes #Platelets #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... hemolysis, deficiency anemia ... Rebound effect from treatment ... : Chronic infections
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach to Anemia ... Sideroblastic anemia ... Macroangiopathic, Infections ... aciduria, Drugs (e.g ... Differential #Diagnosis #hematology
Pediatric SVT - Management Algorithm Identify SVT: • HR not variable • Abrupt rate changes • Infants:
Pediatric SVT - ... Algorithm Identify SVT ... : HR > 180bpm ECG ... SarahFoohey #SVT ... peds #Pediatric #treatment
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