16 results
diagnosis hematology differential algorithm aiha causes hemolysis extravascular intravascular microscopy agglutinin analysis anemias atlas atypical blood bloodcell classification clinical disease
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... : • Autoimmune ... Hemolytic Anemias ... Hemolytic Anemias ... (AHAs) Nonimmune-mediated
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Hemolytic Anemia ... Hemolytic Anemia ... Autoimmune Hemolytic ... #Autoimmune #Hemolytic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... uremic syndrome (HUS ... idiopathic) - Autoimmune ... (AIHA)"Cold" (usually ... (e.g. primary cold
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... AIHA (48-70%) Cold ... MatthewHoMD #Autoimmune ... #Hemolytic #Anemia
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... - Warm vs Cold ... Smear: spherocytes Cold ... #Hemolytic #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Agglutination - Cold ... , aHUS, mechanical ... elliptocytosis, autoimmune ... #Anemia #Differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Warm AIHA • Cold ... AIHA • Alloimmune ... Complement-Mediated • Cold ... anemia • ... MAHA (TTP, DIC, HUS
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... → Sickle Cell anemia ... idiopathic, malignancy, autoimmune ... anemia (TTP, HUS ... #Anemia #Differential
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... azathioprine Cold ... BrighamMedRes #AIHA #Autoimmune ... #Hemolytic #Anemia
Atypical HUS - Hemolytic Uremic Syndrome Unlike typical HUS, which is shigatoxin mediated, aHUS is not typically
Atypical HUS - Hemolytic ... shigatoxin mediated, aHUS ... minus diarrhea (autoimmune ... still present with anemia ... #aHUS #Hemolytic
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