2562 results
REBEL Review 79: Treatment of Hemophilia 

Walkina Out of Pt Room, You Should Know... 
1. Type
REBEL Review 79: Treatment ... Factor Activity ... #hemophilia #hematology ... #management #treatment ... #factorix
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
von Willebrand factor ... Classify severity Treatment ... by a hemophilia treatment ... Diagnosis #Management #treatment ... #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
prolonged if very low factor ... VIII) Treatment ... Disease #Diagnosis #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
supportive care (growth factors ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
validated for VTE treatment ... Anticoagulation #Factors ... #Hematology #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Consumption of Clotting Factors ... Reduced levels of factors ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
patientsl • Risk factors ... : 33% • Treatment ... patients • Risk factors ... : No • Treatment ... Transfusion #Reactions #hematology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
anticoagulant treatment ... Recombinant modified factor ... anticoagulant #hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
PV, MDS, CML) Treatment ... • Treatment is ... with no CV risk factors ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
sites) ↑ Risk Factors ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc