1532 results
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
proteinuria 20.5 g/ ... g or 0.5 g/day → ... g by 12 months ... global (IV-G) ... #rheumatology #nephrology
Albuminuria (Grades) and Risk for CKD
Normal to mildly increased albuminuria:
 - Albumin excretion rate: < 30
ratio: 30-300 mg/g ... ratio: >300 mg/g ... protein: >3.5 g/ ... hypoalbuminemia (<3.0 g/ ... classification #CKD #nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
subnephrotic range (< 3.5 g/ ... proteinuria (> 3.5 g/ ... #Proteinuria #Nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
pernicious anemia) • G-CSF ... Diagnosis #Algorithm #nephrology
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V)
Induction Therapy
methylprednisolone 0.25-1 g/ ... Oral MMF 2-3 g/d ... Regimen) 0.5-1 g/ ... Nephritis #management #nephrology
Hepatorenal Syndrome Treatment
Volume expansion: 
 • Albumin (typical dose = 1g/kg on day 1 +/- day
followed by 20-40 g/ ... management #HRS #nephrology
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
proteinuria > 1 g/ ... LN • MMF 2-3 g/ ... Treatment #management #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
ratio < 15 mEq/g ... ratio > 15 mEq/g ... differential #potassium #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
K+ <13 mEq K+/g ... K+ >13 mEq K+/g ... algorithm #diagnosis #nephrology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
proteinuria - 3.5 g/ ... Cryoglobulinemic #Nephrology