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diagnosis hematology management algorithm ana workup cardiology lupus patterns antibody antibodies arthritis clinical endocarditis erythematosus joint pain pocus pulmonary systemic
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE ... #hematology #rheumatology ... #differential # ... diagnosis #causes
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... #Antibody #Testing ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... erythematosus (SLE ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... in drug-induced SLE ... seen in 30—70% of cases ... Jcortesizaguirr #ANA #Antinuclear ... antibodies #diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Testing - Nuclear ... pattern: • SjS, SLE ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Testing Cytoplasmic ... #Antibody #Testing ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential ... present on repeat testing ... including overnight testing ... (MPA) • SLE ... Proteinuria #Nephrology #Differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... Cytopenia: Common • Immunologic ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... smear, HIV/HCV testing ... test, ANA (e.g., SLE ... Platelet #Disorders #Differential ... #Workup #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... drug-dependent) • Immunologic ... Discontinuation of causal ... Cytopenia: Common • Immunologic ... comparison #table #rheumatology
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