84 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
When present, symptoms ... • "Vasomotor" symptoms ... : • As with ET ... the reduction of symptoms ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... (for secondary APS ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... not as common ... Responsive to Treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... functional ID) Treatment ... improvement in symptoms ... composite endpoint of all-cause ... diagnosis #management #cardiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... neoplasms) • Screen also ... glucocorticoid treatment ... organ-specific signs or symptoms ... Differential #diagnosis #hematology
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
eye; unilateral symptoms ... conditions Diagnosis: Serology ... Culture & GS, PCR Treatment ... diagnosis #management #treatment ... #infectiousdiseases
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Diagnosis: >3 symptoms ... Renal Failure Treatment ... diagnosis #management #hematology
Aphasia - Pathophysiology and Clinical Findings
Broca's Aphasia - Expressive language impairment: non-Fluent
 - Sensory speech areas
Aphasia - Pathophysiology ... motor areas is also ... nearby areas is also ... diagnosis #signs #symptoms ... Brocas #Wernickes #neurology