32 results
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
failure, Addison's disease ... Granulomatous diseases ... calcium)-alkali syndrome ... #differential #diagnosis ... calcium #high #endocrinology
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... - Differential Diagnosis ... , Milk Alkali Syndrome ... , Viral Syndromes ... #Algorithm #Workup
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... #Hypercalcemia ... #Differential #Diagnosis ... #Endocrinology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH
LOW PTH - Hypoparathyroid
 - Congenital (Pediatric)
Hypocalcemia - Differential ... Diagnosis Algorithm ... - Congenital (Pediatric ... Tumor lysis syndrome ... Algorithm #PTH #endocrinology
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... 1) Clinical clues ... #workup #differential ... #diagnosis #endocrinology ... elevated #evaluation #workup
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... Activation: Liver disease ... , Kidney Disease ... - DiGeorge Syndrome ... #endocrinology
Causes of Hypercalcemia due to increased Vitamin D levels
 • The BIG 3:
Causes of Hypercalcemia ... granulomatous diseases ... Genetic: Williams syndrome ... #differential #diagnosis ... #endocrinology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Hyperthyroidism • Paget's disease ... Chronic kidney disease ... • Milk-alkali syndrome ... #Causes #endocrinology ... #diagnosis #differential
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate
LOW PHOSPHATE
 - Low/NormaI PTH
Hypocalcemia - Differential ... Diagnosis Algorithm ... Phenytoin, Nephrotic Syndrome ... Hepatobiliary Disease ... Algorithm #Phosphate #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... wasting crisis & hyperkalemia ... Hirsutism & acne • Infertility ... pathophysiology #genetics #endocrinology ... #peds #pediatrics