72 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophils #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... Conservative/supportive care ... #Management #treatment ... #hematology #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... common • Imaging: CXR ... • Supportive Care ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - ACS, AKI, acute ... organ damage • Treatment ... #TLS #diagnosis ... #management #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... • Supportive care ... progress to MDS or acute ... #management #treatment ... #hematology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... #Differential #Diagnosis ... Classification #Nephrology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... presents as an acute ... • Bicytopenia Treatment ... #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
- Acute Bleeding ... multidisciplinary care ... by a hemophilia treatment ... #Management #treatment ... #hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... for Sweet Syndrome ... (Acute Febrile ... Excellent response to treatment ... #Hematology #Dermatology