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diagnosis treatment arthritis oncology disease joint msk pain algorithm approach blood classification hepatology liver pathophysiology product reactions syndrome aflp anemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Acute hemolysis ... infections, TB, Acute ... Severe trauma, Acute
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... transformation to acute ... leukemia Management ... Conservative/supportive care ... #treatment #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... granules which are ... translocation • Acute ... thrombocythemia • Acute ... Diagnosis #causes #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
• Supportive care ... progress to MDS or acute ... Anemia #diagnosis #management ... #treatment #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Presentation: Subacute-Acute ... : DAH, acute febrile ... initiation • Differential ... , Anaphylaxis, Acute ... #hematology #oncology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... severity Treatment - Acute ... Chronic Management ... multidisciplinary care ... #treatment #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... tumour B cells are ... Treated Like Acute ... pathophysiology #Hematology ... Diagnosis #NonHodgkin #differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... infiltration) Differential ... Support - Critical care ... Liver #Pregnancy #hepatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Chronicity: • Acute ... infections (bacterial), acute ... • Acute = Viral ... Joint #Pain #MSK #rheumatology ... #differential #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... the time course (acute ... MONOARTHRITIS • Acute ... asymmetric pattern Acute ... Diagnosis #MSK #rheumatology
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