68 results
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Low intake • Metabolic ... Renal Losses: • Metabolic ... • HTN, High Aldosterone ... potassium #low #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Hypertensive: • High ... Al, High R - Secondary ... #Hypokalemia # ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Diuretics (late) • High ... hyperaldosteronism • High ... #Primary #Metabolic ... Diagnosis #Algorithm #nephrology
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
) - Gout - Metabolic ... syndrome, Glucose ... ARB, diabetes) ACE ... grade 2-3) - Metabolic ... syndrome, Glucose
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Diagnosis Algorithm High ... Low PTH: • High ... disease, Milk Alkali Syndrome ... disease, Viral Syndromes ... Algorithm #Workup #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... distal tubule. ↑ Nacl ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #nephrology #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Diuretics (late) • High ... hyperaldosteronism • High ... aldosteronism #Metabolic ... Diagnosis #Algorithm #Nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... • Tumor lysis syndrome ... • Metabolic acidosis ... glycosides • High ... blockers - MCW Nephrology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... -> Allantoin (High ... Hypocalcemia • Hyperkalemia ... #TLS #Pathophysiology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... urinary losses: • High ... Pressure: - Metabolic ... Hippurate - Metabolic ... differential #potassium #nephrology