12 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Marcus Gunn Pupil - Relative Afferent Pupillary Defect (RAPD)
Definition: Afferent loop of the pupillary light reflex
the pupillary light ... neuritis due to MS ... Later (1959), Levitan ... with the swinging light ... #Defect #RAPD #neurology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... Type I cryo GN, Light-chain ... deposition disease (light ... Differential #Diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
very high mitotic rate ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
proprioception, and light ... Syndromes #diagnosis #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
Increase => Months later ... tissue => Years later ... Severe, worse at night ... FrozenShoulder #pathophysiology ... stages #staging #msk
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... Decreased heart rate ... within normal limits ... #Pathophysiology
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
palsy OU with a right ... nystagmus in far right ... diagnosed with MS ... Three weeks later ... ophthalmology #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic late-onset ... • Crystalline: light ... Paraproteinemias #Hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Compensated polarized light ... sedimentation rate ... • Hepatitis B serology ... Hepatitis B and C serology