24 results
rheumatology differential management classification dermatology symptoms vasculitis comparison erythematosus hemophagocytic hlh lupus lymphohistiocytosis oncology pathophysiology syndrome systemic table workup activation
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... thin smear • Signs ... node biopsy • Clinical ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Faget's Sign & Liebermeister's Rule Pulse-Temperature Dissociation EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM INFECTIOUS
Faget's Sign & Liebermeister's ... • Malaria • Leptospirosis ... CLINICAL UTILITY ... #Fagets #Sign #Pulse ... #Dissociation #diagnosis
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus Clinical ... Constitutional domain: Fever ... pericarditis • Hematologic ... #SLE #Systemic ... Erythematosus #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... ) General: Fever ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... without other cause ... explain symptoms • Fever ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... disease (10%) : SLE ... #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations
Modified dengue severity classification, PAHO/WHO Dengue without warning signs - DNWS: • Person who lives or has
who lives or has traveled ... days and presents fever ... the following criteria ... organs #dengue #fever ... classification #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
syndromes Clinical ... is the main clinical ... erythematosus [SLE ... Histopathologic criteria ... Activation #Syndrome #Diagnosis
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... conditions: Autoimmune (SLE ... features: Fever ... features: Fever ... in up to 30% of cases
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... Autoimmune diseases: SLE ... Drugs, Unknown cause
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