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differential management dermatology treatment erythematosus lupus sle stills systemic adultonset symptoms vasculitis workup aosd blood dermatomyositis hemophagocytic hlh joint lymphohistiocytosis
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... ’ algorithm • ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Biphasic Illness of Leptospirosis Some patients do not progress to severe disease. Others, rapidly develop severe disease
Biphasic Illness of Leptospirosis ... -14 days): • Fever ... maculopapular rash ... Biphasic #Phases #Diagnosis ... #Illness #Signs
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... includes Kawasaki disease ... erythematous rash ... #Diagnosis #Dermatology ... #Erythematous #Rash
Adult Onset Still's Disease - Yamaguchi Criteria Major criteria: - Fever >= 39C lasting >= 1 weeks
criteria: - Fever ... - Typical skin rash ... with concomitant fever ... Yamaguchi #Criteria #Diagnosis ... #Major #Minor #Rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... • Rheumatic fever ... #differential #diagnosis ... #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... arthritis, Skin rash ... Differential Diaqnoses ... #diagnosis #management ... #treatment #rheumatology
Vesiculobullous Rashes - THE ALGORITHMIC APPROACH Vesiculobullous rashes provoke significant angst in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... and a fever may ... hand-foot-and-mouth disease ... localized lesions and fever ... #Diagnosis #Dermatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... 40% - Fever 36% ... sclerosis, Still's disease ... autoantibodies #signs ... #differential #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Presentation: • Fever ... Conjunctivitis, Mucositis, Rash ... Criteria - Fever ... Polymorphous rash ... KD #vasculitis #rheumatology
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