27 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... : Fever (50%), Depression ... Sjögrens (15%) Skin ... lesions Abdominal pain ... #SLE #systemic
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
• Rheumatic fever ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #joint #pain #skin ... #differential #diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... block • Sjogren syndrome ... diagnosis #rheumatology ... #management
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Scleroderma Thickened skin ... conditions #joint #pain ... #differential #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... #Diagnosis #Management ... #Hematology #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
malaise) - Muscle pain ... Inflammation and pain ... - Lupus - Leukemia ... cutis Diagnosis ... #diagnosis #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... 3rd Decade Skin ... Arthritis: • Joint pain ... #Systemic #Lupus
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Demyelinating Syndrome ... #rheumatology # ... #management #treatment
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Syndrome (SS), ... (SLE), Systemic ... (SLE), Systemic ... #diagnosis #differential
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... 9) Unexplained fever ... #diagnosis #sle ... #clues #system