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diagnosis differential causes workup hypernatremia table diuretics excretion gitelman hypokalemia hypotonic injury kidney medications pathophysiology physiologic rhabdomyolysis treatment volume
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
≥100): SIADH, Renal ... Sodium loss (diuretics ... Present (Uosm <100): Renal ... Hypervolemia with poor renal ... #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... mOsm/kg - Implies renal ... • Euvolemic (Low ... , Ingestion Renal ... #nephrology #sodium
Causes of Hyponatremia - Differential Diagnosis Algorithm Hypovolemia, UNa > 20: • Renal losses, Diuretic excess,
UNa > 20: • Renal ... Bicarbonaturia with renal ... UNa > 20: • Acute ... or chronic renal ... #Causes #nephrology
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Repeat the sodium ... HYPOVOLEMIC • extra-renal ... - fevers • renal ... • renal failure ... #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
- AKI Workup Algorithm ... urinary sediment, renal ... renal biopsy • ... , renal biopsy ... Differential #Diagnosis #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... GI losses • Renal ... especially thiazide diuretics ... • Reduced GFR, AKI ... #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... GI losses • Renal ... especially thiazide diuretics ... • Reduced GFR, AKI ... #Nephrology #Differential
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
Na <20: Extra-renal ... Urine Na >30: Renal ... Urine Na > 30: Renal ... #algorithm #diagnosis ... #sodium #low #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Regulating Renal ... Inhibitors of Renal ... Renal #Excretion ... #Diuresis #Nephrology ... #Pharmacology #
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
• Hypovolemia: Diuretics ... Cirrhosis, Nephrotic Syndrome ... , Chronic Renal ... diagnosis #causes #nephrology ... #sodium #low
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