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diagnosis differential neurology rheumatology sle systemic complications manifestations syndrome vasculitis agammaglobulinemia aids algorithm alzheimersdisease avascularnecrosis centralretinalartery cerebritis classification cns cord
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #Erythematosus ... Complications #pathophysiology ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Fits, Hemiplegia, Ataxia ... pain (20%) Renal disease ... Glomerulonephritis Myositis(5%) Blood ... SLE #systemic #erythematosus ... #signs #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer’s Disease ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... erythematosus ( ... SLE) Signs / Symptoms ... Sjogrens #Syndrome #Pathophysiology ... #Symptoms
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
- Systemic Lupus ... Erythematosus ... syndrome (bulbar symptoms ... - opsoclonus-myoclonus ... Differential #Diagnosis #Causes
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... endothelium) & Decr blood ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... disorders (Systemic lupus ... erythematosus, ... diagnosis #neurology #symptoms ... #signs
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Sickle-cell disease ... Sickle cell disease ... The underlying pathophysiology ... Crisis #Features #Signs ... #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Decr delivery of blood ... inflammation tends to cause ... interstitial lung disease ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
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