11 results
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... Hypersplenism • Secondary ... Normal RBCs • Acute ... Bleed • Hemolysis ... #Differential #
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Disorders • Acute ... (ALL) • Acute ... Leukemia (CML) - Hemolytic ... Anemia - Others
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential ... delayed HTR • Drug-induced ... anemia • ... Acute HTR - Mechanical ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Diagnosis Secondary ... Thrombocytosis): • Acute ... malignancies • Anemia ... iron deficiency, hemolysis ... #secondary
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
suppression (e.g. drugs ... Index > 3: • Acute ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hemolysis, deficiency ... anemia, Rebound ... • Reaction to Medications ... Thrombocytosis #Platelets #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Causes: - Drug ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... - APLS • Acute
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
DiabetesB12 deficiency, Uremia ... Hypothyroidism • Medication-induced ... syndrome, myeloma, secondary ... Fabry's disease, Acute ... Peripheral #Neuropathy #differential
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
epidermal necrolysis, Acute ... interstitial nephritis, Drug ... symptoms syndrome, Hemolytic ... anemia • Avoid ... Prescription #algorithm #management
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
hyperaldosteronism, Secondary ... Conn's, Liddle's), Drugs ... Hypomagnesemia, Acute ... megaloblastic anemia ... #diagnosis #nephrology