66 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... APTT Step 1: Is ... to identify the cause ... ISNeducation #Abnormal ... #diagnosis #hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... the PT and the aPTT ... amyloidosis #Abnormal ... #Causes #diagnosis ... #differential #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Jcortesizaguirr #Abnormal ... #Causes #diagnosis ... #differential #hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PTT, Normal PT ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... mild cases) • ... hemophilia type (e.g ... #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
PT/INR • Normal ... aPTT (prolonged ... factor VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential Diagnosis ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... #Differential #Diagnosis ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... - Differential Diagnosis ... • Secondary (e.g ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology