68 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
the Nephron - Diuretics ... 3) Loop Diuretics ... spironolactone) #Pathophysiology ... #Nephrology #Nephron ... #Diuretics #Hormones
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... perspiration Renal ... • Osmotic diuresis ... Differential #Diagnosis #Causes ... #nephrology #sodium
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Regulating Renal ... Kidney stones caused ... Postoperative abdominal distention ... #Renal #Excretion ... #Diuresis #Nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Villous adenoma Renal ... chewing tobacco, Renal ... #Hypokalemia #Causes ... differential #diagnosis #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... losses, Diuretic ... Ketonuria, Osmotic diuresis ... Diagnosis #Algorithm #Causes ... #nephrology
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
Causes of Polyuria ... a.k.a. osmotic diuresis ... SGLT2 inhibitors (e.g ... Nephrogenic DI (Renal ... #nephrology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Differential Diagnosis Renal ... Causes of Hypomagnesemia ... hypomagnesemia Renal ... transplant, Diuretic ... #nephrology #magnesium
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... GI losses • Renal ... especially thiazide diuretics ... Diagnosis #Algorithm #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... GI losses • Renal ... especially thiazide diuretics ... Diagnosis #Algorithm #Causes