13 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential ... • Extrinsic RBC ... Macroangiopathic, Microangiopathic ... • Intrinsic RBC ... #Anemias #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
syndrome - Thrombotic ... microangiopathy ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... : • Thrombotic ... - Drug-induced thrombotic ... microangiopathy ... #diagnosis #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... Bleed • Hemolysis ... Fragments • Microangiopathic ... Hemolytic Anemias ... Algorithm #Causes #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy ... (TMA) - Differential ... Diagnosis Table ... #TMA #hematology ... #differential #
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Approach to Thrombotic ... Microangiopathy ... (TMA) - Differential ... Initial labs: CBC ... #Microangiopathy
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... Often hard to differentiate ... #Microangiopathy ... Comparison #Diagnosis #Table ... #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Schistocyte: Microangiopathic ... Hemolytic Anemia ... Cold autoimmune hemolytic ... #Morphology #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... spherocytosis, Hemolytic ... uremic syndrome, Thrombotic ... key #diagnosis #differential ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
transform into a RBC ... : Autoimmune, Microangiopathic ... hemolytic anemia ... , Intrinsic RBC ... #anemia #differential