35 results
diagnosis differential algorithm anemia clinical hemolytic management microscopy workup blood classification intravascular plasmodium extravascular falciparum fever macrocytic macrocytosis peripheral product
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC ... Diagnosis #Algorithm #hematology
P. falciparum ring forms on a thin smear - Dr. Christina Dean @deanchr3 #Plasmodium #falciparum #Rings #Smear #Hematology
forms on a thin smear ... falciparum #Rings #Smear ... #Hematology #Microscopy ... #Clinical #Pathology ... #malaria
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... elliptocytosis - RBC ... Infections • Malaria ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... • Intrinsic RBC ... • Infections: Malaria ... Extravascular #Causes ... differential #diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... ↑ LDH • Anti-RBC ... C3d • Blood smear ... 2) LOOK FOR a cause ... management #treatment #rheumatology
Plasmodium Falciparum Blood Smear. Key features suggesting Plasmodium falciparum: - extreme parasitemia - normocytic RBCs (vivax, ovale prefer big
Falciparum Blood Smear ... multiples per RBC ... P. falciparum causes ... ~75% of human malaria ... #microbiology #malaria
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Infections/toxins: Malaria ... Peripheral Blood Smear ... Urobilinogen #Hemolysis ... Differential #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Peripheral blood smear ... Immune mediated hemolysis ... Malaria, Clostridium ... Diagnosis #Algorithm #causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased WBCs ... Normal/lncreased WBCs ... Bleed • Hemolysis ... #Hematology
Plasmodium - Identification Algorithm • P. falciparum: RINGS AND GAMETOCYTES PREDOMINATE, Small delicate rings, <1/3 size
Multiple rings/RBC ... gametocytes • P. malariae ... Identification #Algorithm #pathology ... #smear #microscopy ... #malaria
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