15 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... ) Three syndromes ... child * Severe cases ... #obstetrics #hematology ... diagnosis #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
necrosis HELLP Syndrome ... features: Hemolysis, Thrombocytopenia ... of Pregnancy (AFLP ... obstetrics #hepatitis #comparison ... diagnosis #icp #HELLP #AFLP
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Nephrotic Syndrome ... Heparin-induced thrombocytopenia ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... organ damage • Treatment ... : • Pathophysiology ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... platelet count (thrombocytopenia ... Out Secondary Causes ... IDUS) • Immune Thrombocytopenia ... #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Puncture, EEG Treatment ... CNS #neurology #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... infections/fevers • Thrombocytopenia ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology