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diagnosis differential management symptoms hematology erythematosus lupus neurology systemic vasculitis video causes clinical slitlamp thrombocytopenia treatment antibodies classification iridodonesis iris
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
methotrexate) • Drugs Autoimmune ... • ITP • SLE ... CLL • APLA Alloimmune ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
, autoimmune hepatitis ... microsomal) - Autoimmune ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... diagnosis #table #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... , holster sign, ... anti-synthetase syndrome ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
accompanies other autoimmune ... erythematosus (SLE ... ) Signs / Symptoms ... #Pathophysiology ... #Diagnosis #Signs
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
- Budd Chiari Syndrome ... Erythematosus #SLE ... Complications #pathophysiology ... #signs #symptoms
Iridodonesis Physical examination revealed iridodonesis, or “dancing” of the iris, which was elicited by rapid movement of
movement, is a sign ... with Marfan’s syndrome ... Iris #SlitLamp #PhysicalExam ... #Video #Ophthalmology ... #Signs #Ocular
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 Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... ), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... Thyroid, Autoimmune ... ANA #patterns #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
: ITP, HITT - Autoimmune ... : SLE, RA, antiphospholipid ... syndrome - Pregnancy ... Diagnosis #Framework #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
infection • Autoimmune ... diseases: - 10% SLE ... Often Secondary to Autoimmune ... erythematosus (SLE ... classification #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Demyelinating syndromes ... Thrombocytopenia #Lupus #SLE ... erythematosus #signs ... symptoms #diagnosis #rheumatology
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