23 results
Who to test for BRCA 1/2?
Female Breast Cancer:
 • ≤ 45-50 years at diagnosis
 • Triple
45-50 years at diagnosis ... cancers in this table ... factors in this table ... relative meeting criteria ... #indications #oncology
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
nodular pattern. 1. ... Hypersensitivity pneumonitis ... Hypersensitivity pneumonitis ... #Clinical #Diagnosis ... Differential #Comparison #Table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Myositis: Anti-JO-1, ... RNA Polymerase Ill ... #diagnosis #associations ... #table
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
• Leukocytosis Diagnosis ... - Yamaguchi criteria ... 5 of the below criteria ... should be major: 1. ... #rheumatology #
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
the critically ill ... coagulation defects. 1) ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
the critically ill ... coagulation defects. 1) ... AFLP #obstetrics #hematology ... #diagnosis #table
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... opacities • Diagnosis ... symptoms, or> 1 ... #management #hematology ... #oncology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
- Differential Diagnosis ... Collapse: • Pathophysiology ... heat stress • Criteria ... Multi-system illness: 1. ... temperatures • Criteria
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
-1 and IL-6, leading ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology