24 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... vasculitis • Hematologic ... (MDS) Most met criteria ... for 1) hematologic ... Autoinflammatory #Somatic #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... LAC) • Sjogren Syndrome ... Myositis: Anti-JO-1, ... RNA Polymerase Ill ... Autoantibodies #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... -1 and IL-6, leading ... Histopathologic criteria ... Diagnosis #Management #Hematology ... #Rheumatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... the critically ill ... coagulation defects. 1) ... AFLP #obstetrics #hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
for Sweet Syndrome ... 1. ... 1. ... an underlying hematologic ... #Diagnosis #Hematology
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
Vasculitis 1) ... Hyperviscosity syndrome ... (types II and Ill ... Vasculitis #Diagnosis #Rheumatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... the critically ill ... coagulation defects. 1) ... Obstetrics #OBGyn #Hematology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
5 of the below criteria ... should be major: 1. ... Minor criteria include ... Treatment - Mild ... AOSD #diagnosis #rheumatology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
at > 17 years old ... than females (4:1) ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... signs #psychiatry #criteria
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Criteria for Diagnosis ... : 1. ... withdrawal • Mild ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis