52 results
diagnosis hematology differential causes algorithm comparison nutrition pulmonary thrombocytopenia treatment lupus nephrology oncology sle summary thrombocytosis aflp associations b12 crrt
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... Myelodysplastic syndrome ... cells - G-6-PD deficiency ... Hemolytic uremic syndrome ... #differential #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Gastrectomy, WHDA syndrome ... Tropical sprue, IBD ... #Anemia #Differential ... Algorithm #ferritin #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Acute hemolysis, deficiency ... anemia, Rebound ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD ... Kawasaki, Nephrotic syndrome
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron deficiency ... Megaloblastic: Vitamin B12 deficiency ... , Folate deficiency ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... B12 • Folate deficiency ... Differential #Diagnosis #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 Deficiency ... • Folate Deficiency ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... diagnosis: 70 years old ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #treatment #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Dietary Deficiency ... Myelodysplastic Syndromes ... B12 and Folate Deficiency ... Algorithm #Causes #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
hemolytic-uremic syndrome ... • Severe B12 deficiency ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... differential #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology ... #diagnosis #management
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