14 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... : 70 years old, ... and risk-stratification ... • Risks: infection ... #hematology #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Algorithm Peripheral ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Algorithm Pathophysiology ... High-risk Features ... #Dermatology #Rash ... Color #Targetoid #Algorithm
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... and iron release Diagnosis ... ) Treatment - IV ... showed reduced risk ... #management #cardiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Attempt if high risk ... #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... • Acquired Risk ... • Nephrotic Syndrome ... Venous #Arterial #pathophysiology ... #hematology #differential
Iron Deficiency in Congestive Heart Failure (CHF)

Iron deficiency (ID) in heart failure is a common comorbidity
Exercise capacity Diagnosis ... TSAT < 20% Risk ... depot iron] Treatment ... #pharmacology #pathophysiology ... #cardiology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
• Interstitial Pneumonitis ... effusion, INC risk ... Nephrogenic DI Hematologic ... Malignancy Risk ... Adenocarcinoma Treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Malignancy (e.g. hematologic ... • Acute lupus pneumonitis ... Thrombosis highest risk ... Erythematosus #Diagnosis
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... inflammatory response Risk ... • Metabolic syndrome ... Gout #Comparison #rheumatology