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diagnosis differential nephrology causes acute hyponatremia management treatment kidneyinjury nephrotic renal rhabdomyolysis syndrome anasarca comparison edema erythematosus generalized glomerular hematuria
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Syndrome Step ... hematuria and/or proteinuria ... /nephritic syndromes ... dysmorphic RBCs in urine ... #Algorithm #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... RBC casts, +/- proteinuria ... anti-phospholipid syndrome ... glomerulopathy, radiation nephritis ... , malignant HTN
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... hemolytic-uremic syndrome ... arbitrarily defined as urine ... urine sediment ... #nephrotic #syndrome
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Workup Algorithm ... and signs • Glomerulonephritis ... • Interstitial nephritis ... • Cardio-renal syndrome ... #Workup #Algorithm
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... blood cells on urine ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... range) proteinuria
Causes of Generalized Edema - Differential Diagnosis Algorithm Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Differential Diagnosis Algorithm ... sodium retention, Urine ... • NSAlDs • AKI ... /CKD • Nephrotic ... Oncotic Pressure • Nephrotic
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Syndrome of Inappropriate ... pathology • Malignancy ... Cirrhosis • Nephrotic ... GFR, AKI/CRF Hormonal ... Hypo-osmolar urine
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Syndrome of Inappropriate ... pathology • Malignancy ... Cirrhosis • Nephrotic ... GFR, AKI/CRF Hormonal ... Hypo-osmolar urine
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Differential Diagnosis Algorithm ... • Hepatorenal syndromes ... Drugs • HIV • Malignancy ... Rapidly Progressive Glomerulonephritis ... Acute Interstitial Nephritis
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... inhibitors, hepatorenal syndrome ... enlargement (benign or malignant ... INTRINSINC RENAL Glomerulonephritides ... Acute Interstitial Nephritis
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