26 results
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
platelet aggregation PT ... using INR use PT ... to form clots, ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Cool echo - RV strain, McConnell sign, and CLOT IN TRANSIT!! BP is normal and pt
McConnell sign, and CLOT ... is normal and pt ... Echocardiogram #A4C ... Pulmonary #Embolism #Thrombus ... #Clots #InTransit
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Tests - Prolonged PT ... and Prolonged PT ... Abnormal #APTT #Laboratory ... #Hematology #Diagnosis
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... #Clots #InTransit
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Coagulation Tests PT ... Clotting Time, Thrombin ... Anticoagulation #Testing #Diagnosis ... #Laboratory #Effects
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Prothrombin Time (PT ... Prothrombin Time (PT ... thematttsai #PT ... Thromboplastin #laboratory ... #hematology #diagnosis
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
FVa to generate thrombin ... Thrombin, then primes ... #clot #PT #PTT ... #diagnosis #models ... #hematology #pathophysiology
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
initiation of fibrin clot ... achieve 20 mm clot ... assay representing thrombin-platelet ... Thromboelastography #diagnosis ... #coagulation #hematology
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Step 1: Is the PT ... Heparin, or Direct Thrombin ... Prolonging the PT ... APTT #prolonged #diagnosis ... #hematology #evaluation
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
GI. uterine) Laboratory ... 2B) • Normal PT ... VonWillebrand #Disease #Diagnosis ... #Hematology