23 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... : Acute blood loss ... • Infections: Chronic ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... Infectious: • Acute ... or Chronic Inflammatory ... disorders • Celiac disease ... #Causes #Hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
- Anemia of chronic ... - Anemia of chronic ... kidney disease ... #hematology #diagnosis ... #differential #workup
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Blood Loss ... • Acute Bleed - ... RBCs on Smear • Chronic ... Disease • Marrow ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
kidney disease, ... Acute blood loss ... , Anemia of chronic ... Alcohol use, Liver disease ... diagnosis #causes #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Differential Diagnosis Algorithm ... Acute • Myloid ... T-cell - CD7, CD3 Chronic ... #Disorders #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic Algorithm ... in peripheral blood ... High in acute blood ... #Diagnosis #Workup ... #Hematology #Microcytic
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
the peripheral blood ... • Anemia of chronic ... kidney disease, ... Index > 3: • Acute ... Production #Index #hematology
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.
Algorithm for the ... Causes of acute ... Systemic disease ... leukocytes and occult blood ... #workup #diagnosis
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... Disorders: • Chronic ... translocation • Acute ... Colitis and Crohn’s Disease ... Diagnosis #causes #hematology